Forbidden Sanctums were a popular addition to Path of Exile back in early 2023’s 3.20 update. After a whole league without this feature, it’s finally returned in the core game in update 3.22, but GGG has made some notable changes to it. I have been playing quite a bit of 3.22, and I’ve managed to figure out most of the changes, new best practices, and other things that will help those unfamiliar to get the most out of their Sanctums.

Changes to Sanctum inPoETrial of the Ancestors league

So far, the biggest change is the addition of the Forbidden Tome item. These are sellable, tradeable items that represent both the Sanctum itself and your progress inside it; when you complete the floor, a new item is created representing your progress in the Sanctum, from Boons to Afflictions to how much Resolve you have remaining.

On top of that, the difficulty for later floors was boosted, more Boons and Afflictions were added, and some other tweaks were made to make the Forbidden Sanctums more fun and rewarding. You can also expect a greater variety of hazards in rooms as well as room layouts. Another big change is that Primary defenses can protect Resolve.

Tips and strategies for Forbidden Sanctum inPoE

For those who missed the original Sanctum league in late 2022 to early 2023, Sanctums are basically a self-contained dungeon. You head inside and get Resolve, and every time you are hit by a monster or make an error, you lose some Resolve; once it hits zero, you die and the Sanctum ends.

There are Boons that can raise your Resolve, speed, and other things that might help to get through the Sanctum, as well as Afflictions that have negative repercussions. In order to get all the way through a Sanctum, you need to choose a path through the dungeon based on which Afflictions a room will give.

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All Minor Afflictions in Forbidden SanctumPoE3.22

There are a total of 37 minor afflictions in Forbidden Sanctum in 3.22. They vary in difficulty from freebies to run-ending. Here is a breakdown of everything you need to know about every one of these anti-boons.

All Major Afflictions in Forbidden SanctumPoE3.22

Major Afflictions in the Forbidden Sanctum can be bigger, scarier, and pile on top of the already massive pile of afflictions you are under. Here are all the Major afflictions you can expect to see this season.

Best builds for Forbidden Sanctum inPoE

With all the changes made to Sanctum in 3.22, you may be wondering what some of the best builds would be to get through Tomes with ease. Below are some suggestions to get the most out of Forbidden Sanctums in Trial of the Ancestors.

Related:Best new Keystones in Trial of the Ancestors – Path of Exile 3.22

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For more Path of Exile, check outPath of Exile vs Diablo 4 – Similarities and Differenceson Pro Game Guides.